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Human disease related genes
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UMAP gene cluster
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Keyword
Chromosome
1
2
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5
6
7
8
9
10
11
12
13
14
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MT
Unmapped
X
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External id
Variability
Variable
Not variable
Tissue
Any
Adipose tissue
Brain
Cartilage
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Lymphoid tissue
Male glands
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Mouth
Skin
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Stomach 1
Upper respiratory system
Cluster
1 - Brain neurotransmission
2 - Brain neurotransmission
3 - Brain cellular structure
4 - Brain development
5 - Intracellular signalling
6 - Brain uncharacterized
7 - Retinal
8 - Neurohormonal
9 - Testis spermatogenesis
10 - Housekeeping transcription
11 - Testis uncharacterized
12 - Metabolic
13 - Testis sperm
14 - Low abundant uncharacterized
15 - Testis uncharacterized
16 - Aorta uncharacterized
17 - Cilium structure
18 - Low abundant uncharacterized
19 - Housekeeping mitochondrial
20 - Hormonal
21 - Low abundant uncharacterized
22 - Housekeeping transcription
23 - Cilium structure
24 - Low abundant uncharacterized
25 - Low abundant uncharacterized
26 - Low abundant uncharacterized
27 - Low abundant uncharacterized
28 - Housekeeping mitochondrial translation
29 - Male tissue bacterial defense
30 - Housekeeping structural
31 - Housekeeping uncharacterized
32 - Transport
33 - Lens
34 - Prostate uncharacterized
35 - Low abundant uncharacterized
36 - Receptors uncharacterized
37 - Olfactory bulb
38 - Lung and thyroid development
39 - Kidney transport
40 - Testis
41 - Low abundant uncharacterized
42 - Low abundant uncharacterized
43 - Breast uncharacterized
44 - Housekeeping
45 - Thymus uncharacterized
46 - Skeletal muscle contraction
47 - Spleen uncharacterized
48 - Low abundant uncharacterized
49 - Heart contraction
50 - Muscle contraction
51 - Liver and kidney
52 - Housekeeping
53 - Housekeeping mitochondrial
54 - Interferons
55 - Low abundant uncharacterized
56 - Low abundant uncharacterized
57 - Skin
58 - Immune cells
59 - Squamous epithelium
60 - Not detected
61 - Enzymes and secretion
62 - Squamous epithelium
63 - Small intestine
64 - Gastrointestinal
65 - Epithelium
66 - Housekeeping mRNA
67 - Gastrointestinal
68 - Housekeeping protein processing
69 - Housekeeping
70 - Housekeeping
71 - Housekeeping regulation
72 - Digestive and respiratory defense
73 - Housekeeping cell cycle
74 - Extracellular matrix
75 - Housekeeping
76 - Housekeeping regulation
77 - Housekeeping defense
78 - Lymphoid T cells
79 - Lymphoid myeloid
80 - Heart uncharacterized
81 - Vasculature and connective tissue
82 - Lymphoid B cell
83 - Not detected
84 - Epithelium transcription regulation
Tissue group
Any
Adipose tissue
Adrenal gland
Aorta
Bone marrow
Brain
Breast
Cartilage
Cervix
Choroid plexus
Cornea
Ductus deferens
Dura mater
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart
Kidney
Large intestine
Lens
Liver
Lung
Lymphoid tissue
Male glands
Mesothelial tissue
Mouth
Ovary
Penis
Pineal gland
Pituitary gland
Retina
Salivary gland
Skeletal muscle
Skin
Small intestine
Smooth muscle
Stomach
Synovial tissue
Testis
Thyroid gland
Upper respiratory system
Urinary bladder
Vagus nerve
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Corpus callosum
Hippocampal formation
Hypothalamus
Midbrain
Olfactory region
Pituitary gland
Pons and medulla
Retina
Spinal cord
Thalamus
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Column
Gene
Position
Tissue specific score
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THE PIG PROTEOME
THE PIG ATLAS
TISSUE SPECIFIC PROTEOME
UMAP GENE CLUSTERING
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120 GENES FOUND
Gene
Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
UMAP cluster
Within tissue variation
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Select data columns:
Gene
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Gene
i
Gene name, if available.
Gene synonym (Human ortholog)
Ensembl gene id
Ensembl gene id (Proteincoding human ortholog)
Gene description
Uniprot accession (Human ortholog)
Chromosome
Chromosome position
Related human disease
RNA category pig
Expand
RNA pig tissue group specificity
RNA pig tissue group distribution
RNA pig tissue group specificity score
RNA pig tissue group specific NX
RNA pig brain regional specificity
RNA pig brain regional distribution
RNA pig brain regional specificity score
RNA pig brain regional specific pTPM
Annotation
Expand
UMAP cluster
Within tissue variation
Pig Tissue RNA
Expand
Abdominal adipose tissue [NX]
Adrenal gland [NX]
Amygdala [NX]
Aorta [NX]
Bone marrow [NX]
Breast [NX]
Bronchus [NX]
Bulbourethral gland [NX]
Caudate [NX]
Cecum [NX]
Cerebellum [NX]
Cervix [NX]
Choroid plexus [NX]
Cingulate cortex [NX]
Colon [NX]
Cornea [NX]
Corpus callosum [NX]
Dorsal hippocampus [NX]
Dorsal spinal cord [NX]
Ductus deferens [NX]
Duodenum [NX]
Dura mater [NX]
Ear cartilage [NX]
Endometrium 1 [NX]
Entorhinal cortex [NX]
Epididymis [NX]
Esophagus [NX]
Facial adipose tissue [NX]
Fallopian tube [NX]
Gallbladder [NX]
Heart atrium [NX]
Heart valve [NX]
Heart wall [NX]
Hypothalamus [NX]
Ileum [NX]
Insular cortex [NX]
Jejunum [NX]
Joint cartilage [NX]
Kidney (cortex) [NX]
Kidney (medulla) [NX]
Larynx [NX]
Lens [NX]
Lip [NX]
Liver [NX]
Lung [NX]
Lymph node [NX]
Medulla [NX]
Midbrain [NX]
Motor cortex [NX]
Nasopharynx epithelium [NX]
Occipital cortex [NX]
Olfactory bulb [NX]
Olfactory epithelium [NX]
Oral mucosa [NX]
Ovary [NX]
Penis [NX]
Periaqueductal gray [NX]
Peritoneum [NX]
Pineal gland [NX]
Pituitary gland [NX]
Pleura [NX]
Pons [NX]
Prefrontal cortex [NX]
Prostate [NX]
Putamen [NX]
Rectum [NX]
Retina [NX]
Retrosplenial cortex [NX]
Salivary gland [NX]
Seminal vesicle [NX]
Septum [NX]
Skeletal muscle [NX]
Skin (back) [NX]
Skin (groin) [NX]
Smooth muscle (intestine) [NX]
Somatosensory cortex [NX]
Spleen [NX]
Stomach (lower) [NX]
Stomach (upper) [NX]
Subcutaneous adipose tissue [NX]
Subiculum [NX]
Substantia nigra [NX]
Superior colliculi [NX]
Synovial tissue [NX]
Temporal cortex [NX]
Testis [NX]
Thalamus [NX]
Thymus [NX]
Thyroid gland [NX]
Tongue [NX]
Tonsil [NX]
Trachea [NX]
Urethral gland [NX]
Urinary bladder [NX]
Vagus nerve [NX]
Ventral hippocampus [NX]
Ventral pallidum [NX]
Ventral spinal cord [NX]
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Gene
i
Gene name, if available.
Ensembl
x
Human ortholog
x
Gene description
x
RNA pig tissue group specificity
x
RNA pig tissue group distribution
x
RNA pig tissue group specific NX
x
ADGRD2
ENSSSCG00000005591
ENSG00000180264
Adhesion G protein-coupled receptor D2
Group enriched
Detected in some
adrenal gland:
12.7
brain:
4.1
CCDC42
ENSSSCG00000017988
ENSG00000161973
Coiled-coil domain-containing protein 42A
Group enriched
Detected in some
adrenal gland:
13.8
testis:
34.9
CCDC70
ENSSSCG00000009383
ENSG00000123171
Coiled-coil domain containing 70
Tissue enriched
Detected in some
testis:
71.7
CGA
ENSSSCG00000025434
ENSG00000135346
Glycoprotein hormones alpha chain
Tissue enriched
Detected in some
pituitary gland:
401.1
CHRNA9
ENSSSCG00000024428
ENSG00000174343
Neuronal acetylcholine receptor subunit alpha-9 precursor
Tissue enriched
Detected in some
adrenal gland:
45.9
CNGA2
ENSSSCG00000012753
ENSG00000183862
Cyclic nucleotide gated channel alpha 2
Tissue enhanced
Detected in some
lung:
2.5
pituitary gland:
6.9
upper respiratory system:
2.4
COMMD6
ENSSSCG00000009464
ENSG00000136111
COMM domain-containing protein 6
Tissue enhanced
Detected in all
adrenal gland:
101.6
CYP11A1
ENSSSCG00000025273
ENSG00000140459
Cholesterol side-chain cleavage enzyme, mitochondrial
Group enriched
Detected in some
adrenal gland:
230.0
ovary:
287.1
testis:
79.2
CYP17A1
ENSSSCG00000010591
ENSG00000148795
Steroid 17-alpha-hydroxylase/17,20 lyase
Group enriched
Detected in some
adrenal gland:
453.1
testis:
241.1
DBH
ENSSSCG00000005742
ENSG00000123454
Dopamine beta-hydroxylase
Tissue enriched
Detected in some
adrenal gland:
96.9
DLL3
ENSSSCG00000002987
ENSG00000090932
Delta like canonical Notch ligand 3
Tissue enriched
Detected in some
adrenal gland:
57.4
DMRTA1
ENSSSCG00000005131
ENSG00000176399
DMRT like family A1
Tissue enhanced
Detected in many
pituitary gland:
10.1
FDX1
ENSSSCG00000035945
ENSG00000137714
Adrenodoxin, mitochondrial
Tissue enhanced
Detected in all
adrenal gland:
115.0
ovary:
31.2
testis:
27.6
FDXR
ENSSSCG00000017227
ENSG00000161513
NADPH:adrenodoxin oxidoreductase, mitochondrial
Group enriched
Detected in many
adrenal gland:
79.0
ovary:
21.4
testis:
19.8
FRS2
ENSSSCG00000000493
ENSG00000166225
Fibroblast growth factor receptor substrate 2
Tissue enhanced
Detected in all
adrenal gland:
80.7
GH1
ENSSSCG00000034212
ENSG00000136488,ENSG00000204414,ENSG00000213218,ENSG00000259384
Somatotropin
Tissue enriched
Detected in some
pituitary gland:
738.3
GHRHR
ENSSSCG00000016673
ENSG00000106128
Growth hormone-releasing hormone receptor
Tissue enriched
Detected in some
pituitary gland:
29.1
GPATCH2L
ENSSSCG00000002387
ENSG00000089916
G patch domain-containing protein 2-like
Low tissue specificity
Detected in all
INHA
ENSSSCG00000020771
ENSG00000123999
Inhibin alpha chain
Tissue enriched
Detected in some
ovary:
76.2
INS
ENSSSCG00000033740
ENSG00000254647
Insulin Insulin B chain Insulin A chain
Tissue enriched
Detected in some
adrenal gland:
25.3
INSM2
ENSSSCG00000001949
ENSG00000168348
INSM transcriptional repressor 2
Tissue enhanced
Detected in some
adrenal gland:
13.7
brain:
3.4
lymphoid tissue:
5.7
KIAA1024L
ENSSSCG00000014261
ENSG00000186367
KIAA1024 like
Group enriched
Detected in some
adrenal gland:
9.5
pituitary gland:
16.0
KLHDC7B
ENSSSCG00000000960
ENSG00000130487
Kelch domain-containing protein 7B
Tissue enhanced
Detected in some
cartilage:
2.1
pituitary gland:
3.7
testis:
4.8
LHX3
ENSSSCG00000034657
ENSG00000107187
LIM/homeobox protein Lhx3
Tissue enriched
Detected in some
pituitary gland:
34.8
LIPG
ENSSSCG00000004509
ENSG00000101670
Endothelial lipase precursor
Tissue enhanced
Detected in all
adrenal gland:
49.3
ovary:
56.0
MC2R
ENSSSCG00000039227
ENSG00000185231
Adrenocorticotropic hormone receptor
Tissue enriched
Detected in some
adrenal gland:
59.6
MRLN
ENSSSCG00000032953
ENSG00000227877
Myoregulin
Tissue enhanced
Detected in some
adrenal gland:
13.3
skeletal muscle:
8.1
MSLNL
ENSSSCG00000023487
ENSG00000162006
Mesothelin-like
Tissue enhanced
Detected in some
pituitary gland:
5.1
testis:
3.9
na
ENSSSCG00000003753
PDZK1-interacting protein 1 precursor
Tissue enhanced
Detected in many
adrenal gland:
62.1
kidney:
46.4
ovary:
121.6
testis:
30.0
na
ENSSSCG00000004911
Tissue enriched
Detected in some
pituitary gland:
34.0
na
ENSSSCG00000005756
Group enriched
Detected in some
adrenal gland:
20.7
endometrium:
28.8
na
ENSSSCG00000006719
ENSG00000203857,ENSG00000203859
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 3-beta-hydroxy-Delta(5)-steroid dehydrogenase Steroid Delta-isomerase
Group enriched
Detected in some
adrenal gland:
375.8
ovary:
293.2
na
ENSSSCG00000012524
Tissue enhanced
Detected in some
bone marrow:
1.4
brain:
1.0
pituitary gland:
1.2
stomach:
1.3
na
ENSSSCG00000013329
Tissue enhanced
Detected in some
heart:
3.8
pituitary gland:
9.0
na
ENSSSCG00000021488
ENSG00000206536
Tissue enhanced
Detected in some
adrenal gland:
4.0
pituitary gland:
5.5
na
ENSSSCG00000030140
Tissue enriched
Detected in single
pituitary gland:
5.9
na
ENSSSCG00000031086
ENSG00000104826
Lutropin subunit beta
Tissue enriched
Detected in some
pituitary gland:
196.2
na
ENSSSCG00000031233
Tissue enhanced
Detected in some
adrenal gland:
1.5
pituitary gland:
2.3
testis:
1.6
na
ENSSSCG00000031554
Group enriched
Detected in some
adrenal gland:
1.8
pituitary gland:
5.0
testis:
2.6
na
ENSSSCG00000031563
ENSG00000160882,ENSG00000179142
Tissue enriched
Detected in some
adrenal gland:
437.0
na
ENSSSCG00000031566
Tissue enriched
Detected in some
pituitary gland:
7.9
na
ENSSSCG00000031668
Tissue enhanced
Detected in some
adrenal gland:
1.8
vagus nerve:
1.7
na
ENSSSCG00000032300
Tissue enhanced
Detected in some
adipose tissue:
1.5
adrenal gland:
2.0
large intestine:
1.9
lymphoid tissue:
1.3
pituitary gland:
1.7
na
ENSSSCG00000032307
Tissue enhanced
Detected in some
adrenal gland:
4.1
lymphoid tissue:
1.4
pituitary gland:
2.0
testis:
1.5
na
ENSSSCG00000032363
Tissue enhanced
Detected in single
adrenal gland:
1.0
na
ENSSSCG00000032497
Group enriched
Detected in some
adrenal gland:
6.0
pituitary gland:
6.3
testis:
1.8
na
ENSSSCG00000032598
Tissue enhanced
Detected in some
brain:
1.4
heart:
2.7
synovial tissue:
1.3
na
ENSSSCG00000032817
ENSG00000196578
Group enriched
Detected in some
adrenal gland:
5.4
pituitary gland:
5.4
testis:
2.0
na
ENSSSCG00000032851
ENSG00000170791
Tissue enriched
Detected in some
male glands:
84.9
na
ENSSSCG00000032874
Tissue enhanced
Detected in some
adrenal gland:
9.5
ovary:
4.8
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